Line Probe Assay technology - rapid molecular drug susceptibility test available for the diagnosis of DR-TB

Course content

This hands-on work training was designed by combining the latest evidence and recommendations on rapid molecular diagnostic methods with practical work at the TB Supranational Reference Laboratory in Riga, Latvia

  • Epidemiology of TB, MDR-TB, XDR-TB and TB/HIV.  Social determinants, migrants and other vulnerable groups.
  • Development of DR-TB epidemic on crossroads. Can we prevent development and spread of DR-TB? 
  • National Tuberculosis Program (NTP) perspectives on implementing innovative diagnostics and treatment for MDR-TB.
  • Updates on diagnosis of TB and TB drug resistance.  Proposed TB diagnostic algorithm by the European TB Laboratory Initiative (ELI).    
  • Using of shorter MDR-TB regimens in Europe regions. 
  • TB Laboratory services and laboratory network. 
  • Molecular line probe assays for the detection of mutations associated with resistance to first and second line TB drugs.
  • Internal and external quality control at different diagnostic methods. 
  • Infection control requirement for laboratories at different levels.
  • Drug susceptibility testing for Delamanid and Bedaquiline (Linezolid). 

Target audience

TB Laboratory specialists

Duration and language

5 business days (from Monday to Friday) 

Currently available in Russian language

Training fee

1280 EUR, including training materials, site visit, local transport, catering during working hours/on working days, visa support

Additional costs:

hotel accommodation (from ~ 40 EUR to ~ 80 EUR per night), international flight, visa, reduced per diem